"...has added to the growing ranks of studies finding that antidepressant drugs don't work in people with milder forms of depression"The study looked at 'Minor Depression', which is a DSM diagnosis that is similar to 'Major Depression' except that patients only have 2-4 rather than the 5 or more depressive symptoms necessary for the latter diagnosis.
Neuroskeptic reproduces the 'response rate' figure which shows no significant effect of antidepressants in this diagnosis but I think the findings from the continuous outcomes are more informative:
* See my previous post for an antidepressant medication that is widely recommended and similarly shows a statistically non-significant HRSD score improvement around 1 point.
** The data presented are for random effects but fixed effects produce exactly the same results.
*** To compare with previous studies of major depression, where mean baseline severity is usually around 24 points on the HRSD in these studies they were something like 12 points on the HRSD. If you extrapolate from studies in major depression then baseline severity of this magnitude would fall well within the region of 'no effect' and so the detected effect size of around 1 point is actually larger than you would have expected.