Friday, 6 March 2009

Someone else on anti-depressants and placebo

Nice post on Neuroskeptic looking at a recent meta-analysis of anti-depressants:
After fifty years of research, and untold millions of research dollars, there are hundreds of published clinical trials of antidepressants. It's when you try to make sense of the results of this great mass of trials that the problems become apparent. The latest attempt to do that is a paper from a German-American collaboration, Rief et. al.'s Meta-analysis of the placebo response in antidepressant trials. The authors set out to
Determine overall effect sizes of placebo and drug effects in antidepressant trials
In other words, they wanted to find out how much people improve when given antidepressants, and how much of that improvement is due to the placebo effect.
Read it all.

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